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Give the wound a little time to heal up before working her, once closed, the chances of infection is less. Even if you use a little vet wrap to protect it, it can come off and the wound should be kept clean.
Sounds like a big one. If it is anything like the photo attached, it may haunt you for a while. This one was bad, he had it back in January from a poor transition to barefoot. This summer after it grew out half way, a good 3.5 inch chunk of wall fell off below it. Thankfully he is retired now, but with a horse in work with a missing piece of foot, it can take some fancy shoeing to keep the support that they need.
Best wishes for an uncomplicated recovery.
Erika